Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor Utilized in the therapy of various myeloma. Its synthesis or analyze is important for guaranteeing the purity and security in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug Utilized in the procedure of prostate cancer by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound inside the synthesis of imatinib, a drug that targets specific forms of most cancers, together with chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their examine is significant for optimizing the output system and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty hydrochloride four-5): Lapatinib is employed to deal with breast most cancers, and these intermediates are linked to its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the therapy of breast cancer. Many intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug successful in managing cancers like ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the treatment of colorectal cancer and modest mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have various applications, which include antiviral Homes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for style 5 two diabetes that inhibits the enzyme DPP-4 to manage blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of assorted gluconic acid derivatives, that are used in meals, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication utilized to manage type two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).